This workshop provides an overview on medical population genetics, PLINK and basic statistics and practicals in order to build a foundational knowledgebase for genome wide association testing. The workshop will consist of a series of theory lectures and a “hands on” practical lab session at the end.
This workshop is aimed at H3Africa project members who will be involved in the design and analyses of population data and genome wide association testing and will be able to attend from the West African region within a virtual environment.
After this workshop participants should be able to:
- Conduct genotype calling and association testing
- Conduct population structure and correct for population structure
- Have a good familiarity with PLINK and conducting whole genome data analysis within PLINK
- Have a good background on the theory behind medical population genetics
- Be able to conduct a variety of population genetics statistical tests
Classroom applications
Participant applications
Participants will learn about PLINK, Quality Control and association testing.
Participants are encouraged to work through the following resources to enable them to gain the most from the workshop:
• http://www.ee.surrey.ac.uk/Teaching/Unix/
• http://www.r-tutor.com/r-introduction
• http://onlinestatbook.com/2/introduction/introduction.html
• http://pngu.mgh.harvard.edu/~purcell/plink/
This workshop will only provide a foundation for continued learning in GWAS study design and medical population genetics and will not make you an expert in medical population genetics and genome wide association testing and studies.
Training materials for this course are available as a single downloadable archive here: https://doi.org/10.25375/uct.19129964. Should you re-use any of these materials, please ensure that both the author/s of the material AND H3ABioNet are clearly credited.
