H3ABioNet

Pan African Bioinformatics Network for H3Africa

Postdoctoral Fellowship in Systems Immunology - South African Tuberculosis Vaccine Initiative, University of Cape Town

The South African Tuberculosis Vaccine Initiative performs cutting edge clinical and immunological research in TB pathogenesis and clinical vaccine development. We are inviting applications for a postdoctoral fellowship in systems immunology to conduct research on a large project aimed at identifying and validating immune correlates of risk of TB in collaboration with global leaders in systems biology at Seattle Biomedical Research Institute. The fellow will be based primarily in Cape Town, but the project will include activity-related travel to Seattle. The successful candidate will be responsible for the design, development, and performance of quantitative analysis approaches of complex datasets relating to studies of progression of M. tuberculosis infection to TB disease, as well as vaccination against TB. Responsibilities will also entail developing tools and applying computational models for validating candidate correlates that allow prediction of TB disease risk. For more information on SATVI, visit www.satvi.uct.ac.za, and on Seattle Biomedical Research Institute, visit http://www.seattlebiomed.org.

Key Requirements:

  • Ph.D. degree within the last 5 years in bioinformatics or computational biology, or PhD in biological sciences with at least 3 years of relevant bioinformatics experience.
  • Proficiency in R and/or Python programming.
  • Strong skills in the application of computational and statistical analytical techniques with a focus on high-dimensional and multivariate data analysis.
  • Demonstrated solid scientific proficiency, creativity, critical thinking ability to collaborate effectively with others, and independent thought processes.
  • Authorship of peer-reviewed publications related to bioinformatics or immunology.
  • Ability to handle multiple projects and priorities with exceptional organizational and time management skills.
  • Qualifications and/or previous experience in biological sciences and especially immunology will be advantageous

The candidate should not have held any prior permanent professional or academic positions and must be prepared to comply with the policies, procedures and practices for the postdoctoral sector at the University of Cape Town. The fellowship is initially tenable for three years, but renewal each year will be is contingent on annual progress and performance reviews. The fellowship is valued between R300,000 and R350,000 per year and will depend on relevant experience and skills. The fellowship is compliant with the rules set by the SARS and is exempt from taxation and includes no benefits. No direct service will be required in return for the fellowship.

Potential applicants are encouraged to contact Dr Thomas Scriba, Deputy-Director, Immunology, by e-mail This email address is being protected from spambots. You need JavaScript enabled to view it. prior to application.
To apply, please email a letter of motivation, full CV and contact details of 3 referees, clearly indicating “Postdoctoral Fellowship” in the subject line, to Mrs Keshia Trussel at This email address is being protected from spambots. You need JavaScript enabled to view it. or fax to +27 21 4066693.
Closing date for applications: 31 August 2014.

The original application call is available here.